Motif ID: FOX{D1,D2}.p2

Z-value: 2.085


Transcription factors associated with FOX{D1,D2}.p2:

Gene SymbolEntrez IDGene Name
FOXD1 2297 forkhead box D1
FOXD2 2306 forkhead box D2



Activity profile for motif FOX{D1,D2}.p2.

activity profile for motif FOX{D1,D2}.p2


Sorted Z-values histogram for motif FOX{D1,D2}.p2

Sorted Z-values for motif FOX{D1,D2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{D1,D2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_63478974 4.597 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr4_-_141294682 4.310 NM_018717
MAML3
mastermind-like 3 (Drosophila)
chr17_+_56109940 3.960 NM_001099432
NM_017679
BCAS3

breast carcinoma amplified sequence 3

chr6_-_159386007 3.812 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr6_+_12398514 3.447 NM_001168319
NM_001955
EDN1

endothelin 1

chr14_+_22136968 3.325 NM_022060
ABHD4
abhydrolase domain containing 4
chr2_-_69033515 3.203 NM_182536
GKN2
gastrokine 2
chr1_+_144149794 3.135 NM_006472
TXNIP
thioredoxin interacting protein
chr16_+_54070302 3.088 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr6_-_31658044 2.935 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr2_-_192419896 2.808 SDPR
serum deprivation response
chr8_-_29263714 2.796 NM_001394
DUSP4
dual specificity phosphatase 4
chr3_-_170348215 2.769 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr6_+_149109841 2.763 NM_005715
UST
uronyl-2-sulfotransferase
chr11_-_10630408 2.688 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr2_-_172458970 2.638 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr20_+_62357490 2.608 NM_001104925
NM_018257
PCMTD2

protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2

chr14_+_23937766 2.607 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr1_-_12599934 2.600 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr5_-_42847716 2.537 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr10_-_44794146 2.505 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr6_+_112481970 2.502 NM_003880
NM_198239
WISP3

WNT1 inducible signaling pathway protein 3

chr17_+_64922420 2.486 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr5_+_40877053 2.439 NM_032587
CARD6
caspase recruitment domain family, member 6
chr13_+_109932934 2.438 COL4A2
collagen, type IV, alpha 2
chr6_+_139136349 2.376 NM_015439
CCDC28A
coiled-coil domain containing 28A
chr17_-_36559579 2.374 NM_033188
KRTAP4-5
keratin associated protein 4-5
chr16_+_11966464 2.341 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_183970093 2.275 NM_031935
HMCN1
hemicentin 1
chr2_-_71307705 2.170 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr2_-_151854619 2.048 NM_004688
NMI
N-myc (and STAT) interactor
chr4_-_111339201 2.048 NM_001130721
NM_024090
ELOVL6

ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)

chr6_-_134415311 2.032 NM_145176
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr12_-_28014151 1.967 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr2_-_170138558 1.919 NM_024622
FASTKD1
FAST kinase domains 1
chr6_-_152664906 1.917 SYNE1
spectrin repeat containing, nuclear envelope 1
chr2_-_101457596 1.906 NM_001145664
RFX8
regulatory factor X, 8
chr5_+_90711887 1.882 LOC100129716
hypothetical LOC100129716
chr4_-_74704964 1.882 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr7_+_129693938 1.835 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr13_+_96672705 1.827 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_34262862 1.815 RPL23
ribosomal protein L23
chr2_+_65136989 1.805 NM_015147
CEP68
centrosomal protein 68kDa
chr2_-_192420168 1.795 NM_004657
SDPR
serum deprivation response
chr12_+_12935222 1.793 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr2_+_178893216 1.663 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr2_+_12774264 1.652 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr5_-_159778621 1.648 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr12_+_97513644 1.637 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr6_+_32230172 1.605 PPT2
palmitoyl-protein thioesterase 2
chr20_+_47862782 1.587 SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr20_+_62266217 1.552 MYT1
myelin transcription factor 1
chr20_+_56397568 1.544 NM_001195677
NM_004738
VAPB

VAMP (vesicle-associated membrane protein)-associated protein B and C

chr2_-_73860609 1.538 NM_003584
DUSP11
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
chr22_-_16127520 1.533 CECR3
cat eye syndrome chromosome region, candidate 3
chr14_+_85069217 1.523


chr18_+_27152049 1.522 NM_001942
DSG1
desmoglein 1
chr2_-_68400516 1.520 NM_001111101
NM_015463
CNRIP1

cannabinoid receptor interacting protein 1

chr7_+_116238309 1.515 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_-_165133239 1.512 GRB14
growth factor receptor-bound protein 14
chr8_+_100025806 1.471 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr12_-_51629874 1.471 KRT8
keratin 8
chr14_-_22358752 1.455 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr12_+_46453196 1.451 NM_017842
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr15_+_52092392 1.437 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr1_+_13784553 1.437 NM_001006624
NM_001006625
PDPN

podoplanin

chr20_+_254205 1.436 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr5_-_142046175 1.434 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr16_-_56389176 1.427 NM_001130099
KIFC3
kinesin family member C3
chr20_+_62266270 1.424 NM_004535
MYT1
myelin transcription factor 1
chr10_-_45410197 1.420 NM_001002265
NM_145021
MARCH8

membrane-associated ring finger (C3HC4) 8

chr2_-_134042500 1.384 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr17_+_9686572 1.357 GLP2R
glucagon-like peptide 2 receptor
chr20_+_43943254 1.353 NM_080603
ZSWIM1
zinc finger, SWIM-type containing 1
chr2_+_149119029 1.352 NM_015630
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr11_-_71429747 1.348 NUMA1
nuclear mitotic apparatus protein 1
chr11_-_85074848 1.334 NM_152723
CCDC89
coiled-coil domain containing 89
chr7_-_95063738 1.323 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr1_-_20682541 1.320


chr11_+_10433241 1.316 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr6_+_32229771 1.315 PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr17_-_61655915 1.303 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_-_105817101 1.292


chr11_-_46572073 1.290 AMBRA1
autophagy/beclin-1 regulator 1
chr14_-_30996348 1.285 NM_080664
C14orf126
HEATR5A
chromosome 14 open reading frame 126
HEAT repeat containing 5A
chr3_+_115099007 1.274 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr3_-_71196696 1.267 FOXP1
forkhead box P1
chr17_-_53847937 1.248 RNF43
ring finger protein 43
chr2_-_68952006 1.247 NM_014482
BMP10
bone morphogenetic protein 10
chr14_-_21108714 1.231 NM_001005465
OR10G3
olfactory receptor, family 10, subfamily G, member 3
chr2_-_156897286 1.230 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_-_36719030 1.227 NM_001146182
KRTAP16-1
keratin associated protein 16-1
chr14_+_22911857 1.202 NM_172314
NM_022789
IL25

interleukin 25

chr9_-_72218098 1.201 KLF9
Kruppel-like factor 9
chr7_+_106596641 1.194 NM_012257
HBP1
HMG-box transcription factor 1
chr2_-_96351345 1.194


chr11_+_101488380 1.194 NM_001195045
YAP1
Yes-associated protein 1
chr4_+_124537334 1.187 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr7_+_154351087 1.177 LOC100132707
hypothetical LOC100132707
chr1_-_28376041 1.176 NM_000952
PTAFR
platelet-activating factor receptor
chr2_-_165259334 1.169 COBLL1
COBL-like 1
chr5_+_137701601 1.160 NM_016605
FAM53C
family with sequence similarity 53, member C
chr8_+_40130143 1.154 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr4_-_140443061 1.145 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr20_+_47862656 1.144 NM_015266
SLC9A8
solute carrier family 9 (sodium/hydrogen exchanger), member 8
chr6_+_134800533 1.140 LOC154092
hypothetical LOC154092
chr11_-_101828563 1.120 NM_052932
TMEM123
transmembrane protein 123
chr17_-_36507900 1.114 NM_031960
KRTAP4-8
keratin associated protein 4-8
chr7_-_140270749 1.113 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr16_+_85169615 1.112 NM_005250
FOXL1
forkhead box L1
chr7_+_91408086 1.110 NM_005751
NM_147185
AKAP9

A kinase (PRKA) anchor protein (yotiao) 9

chr2_-_128358903 1.107 NM_031445
AMMECR1L
AMME chromosomal region gene 1-like
chr1_-_166373434 1.098 GPR161
G protein-coupled receptor 161
chr1_+_150753601 1.094 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr7_-_99536214 1.086 NM_182776
MCM7
minichromosome maintenance complex component 7
chr2_+_196229715 1.086 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr2_+_172658453 1.084 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr1_-_151780720 1.080 NM_002962
S100A5
S100 calcium binding protein A5
chr3_-_187309442 1.077 NM_004454
ETV5
ets variant 5
chr8_-_134378630 1.060 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr4_+_109763119 1.055 RPL34
ribosomal protein L34
chr1_-_85816520 1.050 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_-_26058941 1.043 NM_002254
KIF3C
kinesin family member 3C
chr3_+_38322430 1.028 NM_004803
SLC22A14
solute carrier family 22, member 14
chr1_+_87567136 1.027 LMO4
LIM domain only 4
chr6_-_168222645 1.027 NM_024919
FRMD1
FERM domain containing 1
chr17_-_36528113 1.018 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr2_-_213724577 1.015 NM_001079526
IKZF2
IKAROS family zinc finger 2 (Helios)
chr6_+_31081707 1.011 NM_001198815
PBMUCL1
panbronchiolitis related mucin-like 1
chr14_-_34078532 1.005 NM_018453
EAPP
E2F-associated phosphoprotein
chr12_+_123339662 1.004 NM_181709
FAM101A
family with sequence similarity 101, member A
chr9_-_93163965 1.003 AUH
AU RNA binding protein/enoyl-CoA hydratase
chr2_-_197883569 1.001 ANKRD44
ankyrin repeat domain 44
chr20_+_2030527 1.000 NM_080836
STK35
serine/threonine kinase 35
chr6_-_87861492 0.998 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr20_+_31287462 0.995 NM_016583
NM_130852
PLUNC

palate, lung and nasal epithelium associated

chr15_+_78520634 0.991 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_+_204305506 0.991 NM_001123168
FAM72B
FAM72A
family with sequence similarity 72, member B
family with sequence similarity 72, member A
chr2_-_175741096 0.990 NM_001880
ATF2
activating transcription factor 2
chr5_+_137701852 0.983 FAM53C
family with sequence similarity 53, member C
chr11_-_46572160 0.980 AMBRA1
autophagy/beclin-1 regulator 1
chr5_-_158567411 0.977 NM_144726
RNF145
ring finger protein 145
chr5_+_137701855 0.973 FAM53C
family with sequence similarity 53, member C
chr16_-_82707882 0.972 MBTPS1
membrane-bound transcription factor peptidase, site 1
chr6_+_135544214 0.970 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr10_+_63331018 0.970 NM_032199
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr6_-_30151526 0.967 NM_170769
NM_025236
RNF39

ring finger protein 39

chr1_-_28375722 0.967 NM_001164723
PTAFR
platelet-activating factor receptor
chr19_+_17440577 0.966 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr2_+_101680594 0.960 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr15_-_61236532 0.960 NM_015920
RPS27L
ribosomal protein S27-like
chr16_-_46957254 0.953 SIAH1
seven in absentia homolog 1 (Drosophila)
chr10_+_111959978 0.953 NM_001008541
MXI1
MAX interactor 1
chr2_-_188127294 0.951 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_32229599 0.949 NM_005155
PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr4_+_140806536 0.949 MGST2
microsomal glutathione S-transferase 2
chr1_+_40635058 0.941 NM_001198980
SMAP2
small ArfGAP2
chr1_+_51208499 0.941 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr14_+_23654307 0.940 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr6_+_106653429 0.925 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr12_-_46499834 0.913 NM_001098416
NM_015401
HDAC7

histone deacetylase 7

chr3_-_71715431 0.906 NM_001012505
NM_032682
FOXP1

forkhead box P1

chr17_-_60088459 0.905 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr8_+_70567634 0.903 SULF1
sulfatase 1
chr17_-_31616071 0.903 NM_001001418
NM_032258
TBC1D3B
TBC1D3C
TBC1D3G
TBC1D3F
TBC1 domain family, member 3B
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3F
chr5_-_142045770 0.899 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr9_-_93164015 0.894 NM_001698
AUH
AU RNA binding protein/enoyl-CoA hydratase
chr5_+_78567604 0.893 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr20_-_1396336 0.887 NM_016143
NM_018839
NM_182483
NSFL1C


NSFL1 (p97) cofactor (p47)


chr2_+_188865796 0.884 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr11_+_1607580 0.884 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr12_+_105220638 0.881 NM_152772
TCP11L2
t-complex 11 (mouse)-like 2
chr2_-_87156616 0.880 LOC285074
anaphase promoting complex subunit 1 pseudogene
chr16_-_74024750 0.878 NM_006324
CFDP1
craniofacial development protein 1
chr12_-_28016182 0.875 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr3_+_137224266 0.871 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr17_-_31882135 0.870 NM_001001418
NM_001040282
TBC1D3C
TBC1D3G
TBC1D3
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
chr6_+_123152044 0.868 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr20_-_7869068 0.867 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr12_+_91620749 0.865 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr2_+_151974849 0.858 NM_001177665
RIF1
RAP1 interacting factor homolog (yeast)
chr2_+_102602579 0.856 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr20_+_21054623 0.848 NM_001163022
NM_001163023
NM_018474
PLK1S1


polo-like kinase 1 substrate 1


chr4_+_86615275 0.847 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr6_-_56824371 0.846 DST
dystonin
chr6_+_76515690 0.844 MYO6
myosin VI
chr9_+_117955890 0.837 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr16_-_46957284 0.832 NM_001006610
SIAH1
seven in absentia homolog 1 (Drosophila)
chr6_-_105734535 0.831 NM_022361
POPDC3
popeye domain containing 3
chr11_-_102331643 0.831 NM_002427
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr19_-_52426055 0.829 NM_014417
BBC3
BCL2 binding component 3
chr20_+_58064360 0.825 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr2_-_39201631 0.819 SOS1
son of sevenless homolog 1 (Drosophila)
chr9_+_132558972 0.816 NM_014285
EXOSC2
exosome component 2
chr6_+_12120709 0.816 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr12_+_98565663 0.813 NM_153364
FAM71C
family with sequence similarity 71, member C
chr10_-_92671005 0.809 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_-_134809774 0.809 TSC1
tuberous sclerosis 1
chr10_+_21863272 0.803 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr20_-_49612574 0.803 NM_001136021
NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.